One of the major objectives in systems biology is to understand the relation between the topological structures and the dynamics of biological regulatory networks.In this context, various mathematical tools have been developed to deduct structures of regulatory networks from microarray expression data.In general, from a single data set, one cannot
Abnormal mechanical stress on bicuspid aortic valve induces valvular calcification and inhibits Notch1/NICD/Runx2 signal
Background Bicuspid aortic valve (BAV) is a congenital cardiac deformity, increasing the risk of developing calcific aortic valve disease (CAVD).The disturbance of hemodynamics can induce valvular calcification, but the mechanism has not been fully identified.Methods We constructed a finite element model (FEM) of the aortic valve based on the compu
Review: Sumber dan Pemanfaatan Zat Warna Alam untuk Keperluan Industri
ABSTRAKPada umumnya pewarna sintetis memiliki beberapa keunggulan antara lain; jenis warna beragam dengan rentang warna luas, ketersediaan terjamin, cerah, stabil, tidak mudah luntur, tahan terhadap berbagai kondisi lingkungan, daya click here mewarnai kuat, mudah diperoleh, murah, ekonomis, dan mudah digunakan.Namun demikian penggunaan pewarna sin
Liberalisation and Value Extraction. The Trajectory of Railways in the Neoliberal State
The expansion of financial capitalism towards the "lower levels" of economic life (or the foundational economy [Bowman et al.2014]) is fostered by the privatisation of utilities and outsourcing of pub-lic services, under the encouraging banner of liberalisation.Our paper aims to describe some aspects of this transformation and its implications for
Silver (I) N-Heterocyclic Carbenes Carbosilane Dendritic Systems and Their Imidazolium-Terminated Analogues as Antibacterial Agents: Study of Their Mode of Action
Spherical dendrimers and dendrons containing silver(I) N-heterocyclic carbenes (Ag(I)-NHC) and additionally bow-tie metal-free dendritic systems were synthesized in a simple and straightforward synthetic procedure royal nomadic 5413 rug and subsequently characterized.The antibacterial activity was evaluated, and in parallel, a comparative study wit